NATIONAL OPEN UNIVERSITY OF NIGERIA
14/16 AHMADU BELLO WAY, VICTORIA ISLAND, LAGOS
SCHOOL OF SCIENCE AND TECHNOLOGY
MARCH/APRIL 2014 EXAMINATION
COURSE CODE: BIO 301
COURSE TITLE: GENETICS II
TIME ALLOWED: 2 HOURS
INSTRUCTION: ANSWER ANY FOUR QUESTIONS
1ai.What do you understand by the term pedigree?
ii. Explain why sickle cell anemia is regarded as a heritable disease.
bi. Describe the structure of a virus.
ii. List the characteristic features of haploid plants.
2ai. List the general steps of the lytic cycle.
ii. Discuss the various methods by which polyploidy can be induced.
bi. Describe the antibodies and blood antigens relationships in ABO blood group.
ii. Explain the defects of abundant and structural proteins.
3ai. Define genetic transfer.
ii. How can you tell if there are any mutant colonies in a culture?
b. Write short notes on the following:
(i) Karyotype (ii) Codominance (iii) dosage compensation.
4ai. State the Haldane’s Rule.
ii. Describe hybrid sterility giving examples.
bi. What do you understand by genetic polymorphism?
ii. Describe the mechanisms of balancing selection.
5ai. What do you understand by the term paralogous?
ii. Explain the defects of abundant and structural proteins.
b. Write short notes on the following:
i. Homologous ii. Homoeologous iii. Paleopolyploidy
6ai.Enumerate the role of structural chromosomal aberrations in plant breeding.
ii. Describe the mode of occurrence of the different types of inversions you know.
b. Write short notes on the following:
i. Gene recombination ii. Gene transfer iii. Frameshift mutation
You can get the exam summary answers for this course from 08039407882
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