CHM421 Tma – Heterocyclic Chemistry

CHM421
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1. Quinine is a chemical that offer the following except,,,,,,,

antimalarial

antipyretic

antiinflammatory

antibacterial

2. The main constituent starting materials for the synthesis of quinoline by Skraup method are ….

Aniline and Acrolein

Acid and aniline

Acrolein and benzene

Benzene and Acid

3. Quinoline nucleus has been found in some group of alkaloids notably …….

tropane

quinine

psilocybin

morphine

4. The extraction of quinoline first took place in …………

1983

1843

1834

1934

5. O-aminobenzaldehyde react with an aldehyde or ketone in a basic medium leading to the formation of quinoline. This process depict that prsented by

Doebner-Miller

Skraup

Conrad-Limpach

Friedlander

6. The main use of quinoline is towards the synthesis of ………..

Nicotinic acid

Benzoic acid

Nitric acid

Formic acid

7. In Doebner-Miller synthesis of quinoline, the main starting material is the

-unsaturated carbonyl compounds

-unsaturated carbonyl compounds

-unsaturated carbonyl compounds

-unsaturated carbonyl compounds

8. It has been reported in 2005 that the production of quinoline worldwide amount to ……tonnes

5

4

5

7

9. The reaction between -keto esters and aniline to produce quinoline is typical of …… method

Doebner-Miller

Skraup

Conrad-Limpach

Friedlander

10. The trade name

pyridine-1,3-dicarboxylic acid

pyridine-2,6-dicarboxylic acid

pyridine-2,3-dicarboxylic acid

pyridine-1,6-dicarboxylic acid

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